Patent · US Active

Engineered PD-1 variants

US11905322B2 · kind B2 · utility

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2References
19Claims
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Key dates

Filing dateMay 3, 2021
Grant dateFeb 20, 2024
Priority date—
Expiry dateSep 16, 2041

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2319/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Isolated polypeptides comprising engineered mutant PD-1 polypeptide are provided, as are fusion polypeptides comprising the mutant and methods of use thereof. Bispecific PD-L1 and PD- L2 binding mutant PD-1 polypeptides are provided. PD-L2-specific binding mutant PD-1 polypeptides are also provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.