Compositions and methods for molecular memory storage and retrieval
US11905532B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Jun 25, 2020 |
| Grant date | Feb 20, 2024 |
| Priority date | — |
| Expiry date | Feb 21, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2795/14152
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Compositions and methods for the storage, organization, access, and retrieval of information encoded by sequence controlled polymers such as data storage nucleic acids are provided. In some embodiments, organization, storage, and/or selective retrieval of the data is facilitated by hybridization of barcode sequence of the sequence controlled polymer to the reverse complementary sequence of an oligonucleotide. The plurality of oligonucleotides can be arrayed using a known organization scheme, and selectively capture and localize the corresponding sequence controlled polymer. In some embodiments, the compositions and methods utilize recombinant bacteriophage, typically featuring a minigenome having a bacteriophage origin of replication and packaging signal separated from a data storage sequence by barcodes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.