Process for preparing a drug delivery composition
US11911476B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 25, 2018 |
| Grant date | Feb 27, 2024 |
| Priority date | — |
| Expiry date | Jul 31, 2039 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB29K2105/0085
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to process for preparing a drug delivery composition comprising the steps of a) preparing a masterbatch comprising a drug and a first polymer by (i) extruding the first polymer, wherein said first polymer has a melting temperature below 140° C.; and (ii) introducing the drug during extrusion of the first polymer, with a drug content between 0.1% and 90%, based on the total weight of the masterbatch; and b) introducing the masterbatch in a polymer-based matrix during production of the drug delivery composition, wherein step a) is performed at a temperature at which the first polymer is in a partially or totally molten state, and step b) is performed at a temperature at which both the first polymer and at least a polymer of the polymer-based matrix are in a partially or totally molten state.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.