Scaffolds and multifunctional intermediates for imaging PSMA and cancer therapy
US11911488B2 · kind B2 · utility
0Cited by
1References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 4, 2020 |
| Grant date | Feb 27, 2024 |
| Priority date | — |
| Expiry date | Sep 3, 2040 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K49/0019
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Carbamate and beta-amino acid urea-based scaffolds that have high binding affinity to PSMA are disclosed. These scaffolds can be radiolabeled and used for imaging cells and tumors that express PSMA or for cancer radiotherapy. These compounds also can comprise a fluorescent dye and be used for imaging cells and tumors that express PSMA or for photodynamic therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.