Tumor bed implant for multimodality treatment of at risk tissue surrounding a resection cavity

US11911631B2 · kind B2 · utility

Assignees

• Thomas Jefferson University · US
• DREXEL UNIVERSITY · US

Inventors

• Paul Stauffer · Durham, US
• Voichita Bar-ad · Wynnebrook Manor, US
• Mark Hurwitz · Narberth, US
• Adam Luginbuhl · ندا, US
• Michele Marcolongo · Chester, US
• Dario Rodrigues · Philadelphia, US
• David Cognetti · Penn Valley, US
• Joseph Curry · Hillside, US
• Katsiaryna Prudnikova · Huntingdon Valley, US

Key dates

• Filing date: Mar 31, 2017
• Grant date: Feb 27, 2024
• Expiry date: Mar 31, 2037

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61N2005/1024
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A device having a biocompatible polymer as a body and regularly spaced radiation seeds and regularly spaced magnetic materials disposed of within the body of the biocompatible polymer, or uniformly distributed liquid radiation and magnetic fluid materials within a polymer slab, hollow thick wall polymer shell, or thin wall polymer balloon, as suitable for surgical placement within a resection cavity for treatment of at-risk tissue in the tumor margin with local hyperthermia in combination with radiation and potentially also with chemotherapy and/or immunotherapy that is slowly released from the biocompatible polymer.