Polyanionic acids to improve recovery and minimize system loss
US11912983B2 · kind B2 · utility
0Cited by
6References
15Claims
0Family size
Assignee
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Key dates
| Filing date | Dec 4, 2020 |
| Grant date | Feb 27, 2024 |
| Priority date | — |
| Expiry date | Feb 3, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/8836
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present technology relates to a method of separating a sample comprising oligonucleotides. The method includes injecting a polyphosphonic acid at a concentration of between about 0.01 M to about 1 M into the sample comprising oligonucleotides. The method also includes flowing the sample and polyphosphonic acid through a liquid chromatography column and separating the oligonucleotides.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.