Topical formulation of hyperbranched polymer-coated particles
US11918695B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 11, 2016 |
| Grant date | Mar 5, 2024 |
| Priority date | — |
| Expiry date | May 11, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/654
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Core-shell particles have a hydrophobic core and a shell formed of o containing hyperbranched polymers (HP). The HP can be covalently bound to the one or more materials that form the core or coated thereon. The HP coating can be modified to adjust the properties of the particles. For example, unmodified HP coatings resist non-specific protein absorption. Alternatively, the hydroxyl groups on the HP coating can be chemically modified to form functional groups that react with functional groups on tissue to adhere the particles to the tissue, cells, or extracellular materials, such as proteins. Such functional groups include, but not limited to, aldehydes, amines, and O-substituted oximes. Topical formulation for application to the skin contain these HP coated nanoparticles. In some embodiments, the particles include cosmetic, therapeutic, diagnostic, nutraceutical, and/or prophylactic agents, such as those used as sunblock compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.