Methods for characterizing loss of antigen presentation

US11920194B2 · kind B2 · utility

Assignees

• BIONTECH SE · DE
• TRON—Translationale Onkologie an der Universitätsmedizin der Johannes Gutenberg-Universität Mainz · DE

Inventors

• Ugur Sahin · Mainz, DE
• Martin SUCHAN · Mainz, DE
• Barbara Schrörs · Mainz, DE
• Martin Löwer · Bodenheim, DE
• Petra OEHM · Mainz, DE

Key dates

• Filing date: Jun 1, 2018
• Grant date: Mar 5, 2024
• Expiry date: Nov 27, 2038

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q2600/156
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

This invention relates to methods for screening for a genotype for loss of antigen presentation via MHC class I in a subject and/or respectively detecting a subject's increased risk of resistance against immunotherapy such as against vaccination.