Single-molecule sequence and high sensitivity methylation analysis for tissue-specific analysis
US11920201B2 · kind B2 · utility
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Key dates
| Filing date | Jan 23, 2018 |
| Grant date | Mar 5, 2024 |
| Priority date | — |
| Expiry date | Jul 26, 2038 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided herein are methods of determining one or more modification(s) of the nucleic acid sequence of at least one nucleic acid and at least one epigenetic alteration of the at least one nucleic acid in a sample of a subject. The sample is derived from a body fluid of the subject. The methods link the one or more modification(s) to a specific cell type.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.