Control material and methods for cell analyzers
US11921104B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 28, 2021 |
| Grant date | Mar 5, 2024 |
| Priority date | — |
| Expiry date | Jun 28, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2496/10
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This disclosure relates to verifying the operation of cell analyzers, including microscope-based cell imaging and counting analyzers. In one general aspect, a mixture of micro-beads having known characteristics is introduced into the analyzer. One or more images of the mixture are acquired with the analyzer's microscope, the images are analyzed, and a determination is made about whether results meet one or more predetermined quality control thresholds. Also disclosed is a hematology control material that can be used to perform the verification and includes a solvent, a dye dissolved in the solvent, and micro-beads suspended in the solvent. In another general aspect, a quality control method for the analyzers includes capturing images of samples that include patient cells using at least a microscope, extracting sample-specific information about properties of the patient samples from the images, and testing information from the samples against predetermined standards to verify the operation of the analyzer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.