Patent · US Active

Pyrazole pyrimidine derivative and uses thereof

US11925641B2 · kind B2 · utility

0Cited by

3References

19Claims

0Family size

Assignee

YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. · IL

Inventors

Yinon Ben-Neriah · Nesher, IL
Guy Brachya · Jerusalem, IL
Ido Burstain · Sderot, IL
Waleed Minzel · Kfar Kanna, IL
Irit Snir-Alkalay · Mevaseret Tsiyon, IL
Joseph P. Vacca · Telford, US
Dansu Li · New York, US

Key dates

Filing date	Mar 29, 2021
Grant date	Mar 12, 2024
Priority date	—
Expiry date	Dec 6, 2041

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D413/14
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides pyrazole pyrimidine derivatives which inhibit Casein kinase I (CKI) and/or Interleukin-1 receptor-associated kinase 1 (IRAKI) and methods of their manufacture, compositions comprising them and uses thereof in methods of treating malignant disease and disorders and methods for treating inflammatory diseases and disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.