Patent · US Active

Processes for the preparation of selective estrogen receptor degraders

US11926634B2 · kind B2 · utility

0Cited by

2References

20Claims

0Family size

Assignee

ELI LILLY AND COMPANY · US

Inventors

Alonso Jose ARGUELLES DELGADO · Indianapolis, US
Boris Arnoldovich CZESKIS · Carmel, US
Mai Khanh Nguyen HAWK · Indianapolis, US
Douglas P. Kjell · West Lafayette, US
Yu Lu · Indianapolis, US
Nicholas Andrew Magnus · Indianapolis, US
David Michael Remick · Indianapolis, US

Key dates

Filing date	Jan 27, 2023
Grant date	Mar 12, 2024
Priority date	—
Expiry date	Jan 27, 2043

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07F5/022
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Disclosed are methods of making selective estrogen receptor degraders (SERDs) of Formula A, as well as intermediates thereof, salts thereof including a pharmaceutically acceptable salt, and pharmaceutical compositions thereof: wherein either R1 or R2 is independently Cl, F, —CF3, or —CH3, and the other is H; and R7 is H or PG.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.