Methods and systems for screening therapeutic compositions for treating age-related macular degeneration
US11927590B2 · kind B2 · utility
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13Claims
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Key dates
| Filing date | Jun 11, 2021 |
| Grant date | Mar 12, 2024 |
| Priority date | — |
| Expiry date | Feb 3, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/502
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods and systems for screening therapeutic compositions for the treatment of age-related macular degeneration (AMD) or for the prevention of progression of AMD, wherein retinal pigment epithelium cells (RPE) are cultured and the level of hypoxia-induced exosome release from the RPE cells is subsequently measured. In the present invention, the level of hypoxia-induced exosome release can be correlated with AMD onset and severity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.