Multidimensional sample separation with pressure adjustment
US11933769B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 30, 2019 |
| Grant date | Mar 19, 2024 |
| Priority date | — |
| Expiry date | Jan 23, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N30/468
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A multidimensional sample separation apparatus includes a first separation dimension for separating a fluidic sample, a second separation dimension for further separating the fluidic sample, a switching mechanism, and a control unit. The first separation dimension includes a first fluid drive unit and a first sample separation unit. The second separation dimension includes a second fluid drive unit for driving the separated fluidic sample, and second and third sample separation units each configured for further separating the separated fluidic sample. The switching mechanism is configured for selectively switching an outlet of the first separation dimension in fluid communication with a selected one of the second sample separation unit and/or the third sample separation unit. The control unit is configured for controlling a pressure at inlets of the second sample separation unit and the third sample separation unit to be substantially the same at least at the time of the switching.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.