Automated chromatography column switching control based on pressure detection
US11938418B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Dec 15, 2015 |
| Grant date | Mar 26, 2024 |
| Priority date | — |
| Expiry date | Jan 2, 2039 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/889
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
Certain embodiments of the invention provides a method for monitoring level of saturation of a chromatography media in a column, which method comprises measuring a first pressure at the inlet of an unloaded column; measuring a second pressure at the inlet from a loaded column; and comparing the first and second pressure measurement to determine the level of saturation of the chromatography media. Embodiments of the invention also provide related methods for controlling a chromatography system and methods for controlling a periodic counter current chromatography system, as well as a chromatography system suitable for use with the novel methods.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.