Transgenic microalgae and use thereof as a feed for delivery of interfering RNA molecules
US11939576B2 · kind B2 · utility
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Key dates
| Filing date | Aug 26, 2020 |
| Grant date | Mar 26, 2024 |
| Priority date | — |
| Expiry date | Feb 11, 2042 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A40/146
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides non-propagating transgenic microalgae expressing at least one heterologous RNAi molecule. The RNAi-expressing non-propagating transgenic microalgae are used for oral delivery of the RNAi molecule to a target organism in its intact and functional form. The heterologous RNAi molecule, present within the microalgae, is characterized by being biologically active, exerting at least one specific effect on the organism consuming the microalgae or on a pathogen of said organism. In particular, the non-propagating transgenic microalgae are used as agents for biological control of animal and plant pests.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.