Cutinase having improved enzymatic activity
US11939603B1 · kind B1 · utility
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5Claims
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Key dates
| Filing date | Jun 21, 2023 |
| Grant date | Mar 26, 2024 |
| Priority date | — |
| Expiry date | Jun 21, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y301/01074
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A modified cutinase is disclosed. The cutinase has the modified amino acid sequence of SEQ ID NO: 2, wherein the modification is a substitution of asparagine at position 181 with alanine, or substitutions of asparagine at position 181 with alanine and phenylalanine at position 235 with leucine. The modified enzyme has improved PET-hydrolytic activity, and thus, the high-activity PET hydrolase is obtained, and the industrial application value of the PET hydrolase is enhanced.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.