Compositions and methods for enforcing fucosylation of lactosaminyl glycans in human cells with alpha(1,3)-fucosyltransferases
US11939616B2 · kind B2 · utility
0Cited by
0References
4Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Sep 22, 2020 |
| Grant date | Mar 26, 2024 |
| Priority date | — |
| Expiry date | Nov 2, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y204/01214
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present disclosure provides, inter alia, compositions and methods for enforcing a pattern of cell surface fucosylated lactosaminyl glycans on a human cell. In certain embodiments, the compositions and/or methods utilize one or more members of the α(1,3)-fucosyltransferase family. In certain embodiments, a process for custom-modifying a fucosylated lactosaminyl glycan on a human cell is disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.