tRNA/pre-miRNA compositions and use in treating cancer
US11946049B2 · kind B2 · utility
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16Claims
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Key dates
| Filing date | May 21, 2019 |
| Grant date | Apr 2, 2024 |
| Priority date | — |
| Expiry date | Oct 10, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/531
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are hybrid tRNA/pre-miRNA molecules, e.g., comprising a single tRNA and one, two or more pre-miRNA molecules, useful for the production and therapeutic delivery of an inserted RNA sequence, e.g., one or more miRNAs. Also provided are liposomes and nanoparticles that include the hybrid tRNA/pre-miRNA molecules. Methods of treating cancer by administration of the hybrid tRNA/pre-miRNA molecules are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.