Methods for overcoming glucocorticoid resistance and for determining glucocorticoid resistance potential in cancer
US11946053B2 · kind B2 · utility
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22Claims
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Key dates
| Filing date | Oct 2, 2019 |
| Grant date | Apr 2, 2024 |
| Priority date | — |
| Expiry date | Aug 9, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides methods for overcoming glucocorticoid resistance of cancers by inhibition of CASP1. Also disclosed are diagnostic methods for determining glucocorticoid resistance potential by measuring expression level or promoter methylation status of CASP1 gene and/or NLRP3 gene.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.