Method of reinforcing efficacy of stem cells using ethionamide
US11946070B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 15, 2020 |
| Grant date | Apr 2, 2024 |
| Priority date | — |
| Expiry date | Jan 8, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2501/999
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a medium composition for reinforcing the efficacy of stem cells, including ethionamide, a method of reinforcing the efficacy of stem cells, including culturing stem cells in the medium composition, a method of preparing stem cells with reinforced efficacy, stem cells prepared by the above-mentioned method, and a use thereof. According to the present invention, the anti-inflammatory effect of mesenchymal stem cells and expression levels of paracrine factors may be effectively improved by a simple method of treating mesenchymal stem cells with ethionamide, and the stem cells obtained by the above method may be effectively used for preventing or treating an inflammatory disease or a degenerative brain disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.