Aripiprazole sustained-release microsphere and preparation method therefor
US11951104B2 · kind B2 · utility
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4Claims
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Key dates
| Filing date | Jun 8, 2018 |
| Grant date | Apr 9, 2024 |
| Priority date | — |
| Expiry date | Mar 19, 2040 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/38
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides an aripiprazole sustained-release microsphere and a preparation method therefor. The microsphere comprises aripiprazole and polylactide-glycolide. The microsphere is of a spherical reticular skeleton structure, with reticular micropores distributed in the spherical surface, and aripiprazole filled in the micropores. The average particle diameter of the microsphere is less than 20 μm, and is suitable for a 5 gauge needle. The content of aripiprazole is 65%-80% of the total weight of the microsphere.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.