Modification of gene transcription and translation efficiency by 5′UTR sequence variation
US11951120B2 · kind B2 · utility
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20Claims
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Key dates
| Filing date | Dec 7, 2022 |
| Grant date | Apr 9, 2024 |
| Priority date | — |
| Expiry date | Dec 7, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/20034
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to the fields of mRNA vaccines, mRNA therapy, and gene therapy and specifically to the use of gene expression vectors or PCR amplicons containing various 5′UTR sequences followed by coding sequences for in vitro and in vivo production of mRNA or proteins of interest.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.