Patent · US Active

Stabilization of glucagon by trehalose glycopolymer nanogels

US11951176B2 · kind B2 · utility

0Cited by

0References

17Claims

0Family size

Assignee

The Regents of the University of California · US

Inventors

Heather D. Maynard · Los Angeles, US
Natalie Boehnke · Los Angeles, US

Key dates

Filing date	Nov 30, 2018
Grant date	Apr 9, 2024
Priority date	—
Expiry date	Apr 11, 2040

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC08F2810/20
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Trehalose-based nanogels for stabilizing and controlled releasing biomolecules such as glucagons are disclosed. Specifically, trehalose-based nanogels comprise (a) a copolymer comprising first methacrylate units and second methacrylate units, wherein (i) the first methacrylate units comprise trehalose side chains; and (ii) the second methacrylate units comprise disulfide side chains; (b) dithiol cross-linkers; wherein the dithiol cross-linkers cross link the copolymer through the disulfide side chains of the second methacrylate units.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.