High sterol-containing lipid nanoparticles
US11951177B2 · kind B2 · utility
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19References
16Claims
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Key dates
| Filing date | Mar 22, 2023 |
| Grant date | Apr 9, 2024 |
| Priority date | — |
| Expiry date | Mar 22, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure provides a lipid nanoparticle comprising: a nucleic acid cargo molecule; sterol or a derivative thereof present at elevated content; neutral lipid; an ionizable lipid; and a hydrophilic polymer-lipid conjugate present at a content between 0.5 and 3 mol %, wherein each mol % content is relative to total lipid present in the lipid nanoparticle.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.