Patent · US Active

Anti-cancer nuclear hormone receptor-targeting compounds

US11952349B2 · kind B2 · utility

2Cited by
21References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 12, 2020
Grant dateApr 9, 2024
Priority date
Expiry dateNov 12, 2040

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07J71/0047
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The disclosure relates to anti-cancer compounds derived from a payload which binds to poly(ADP-ribose) polymerase (PARP) and a nuclear steroid-targeting epitope (B of Formula I), which components are covalently linked via a linker, to products containing the same, as well as to methods of their use and preparation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.