Patent · US Active

Fluidic devices for closed cell culture applications under current good manufacturing practice

US11958050B2 · kind B2 · utility

0Cited by
1References
14Claims
0Family size

Inventor

Key dates

Filing dateMay 21, 2019
Grant dateApr 16, 2024
Priority date
Expiry dateJun 12, 2042

Classification

  • Technology area (CPC B)Performing Operations; Transporting
  • CPC primaryB01L2400/049
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A system and method for automated and closed cell culture system. The system includes a disposable assembly, actuators, sensors, software/firmware and smart device App. The disposable includes fresh media, drug or reagents containers, waste container, sample out containers, cell culture flask, well, bag or bioreactor and active or passive pumping elements. The system is expanded to multiple containers cell or organ processing. In all these precisely controlling the fluids are achieved by interdigitated differential capacitance measurements. The system has provision for imaging, machine vision control, controlled over the internet, volume metering and can use wide variety of pumps for actuation. The system is programmed to perform cGMP protocols and operated as a portable instrument.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.