Method for inducing pluripotent stem cells to differentiate into somatic cells
US11959103B2 · kind B2 · utility
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Key dates
| Filing date | Nov 9, 2017 |
| Grant date | Apr 16, 2024 |
| Priority date | — |
| Expiry date | Jul 21, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/90
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided is a method for inducing pluripotent stem cells to differentiate into somatic cells in a culture medium containing a heparin binding growth factor, the method comprising bringing cells into contact with a conjugate of a laminin E8 fragment and a growth factor binding domain-containing fragment of a heparan sulfate proteoglycan. According to the present invention, pluripotent stem cells can be induced to differentiate into any desired somatic cells in a highly efficient manner.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.