Artificial intelligence-based determination of analyte data for base calling
US11961593B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 17, 2021 |
| Grant date | Apr 16, 2024 |
| Priority date | — |
| Expiry date | Nov 17, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06V2201/03
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
The technology disclosed relates to artificial intelligence-based determination of analyte data for base calling. In particular, the technology disclosed uses input image data that is derived from a sequence of images. Each image in the sequence of images represents an imaged region and depicts intensity emissions indicative of one or more analytes and a surrounding background of the intensity emissions at a respective one of a plurality of sequencing cycles of a sequencing run. The input image data comprises image patches extracted from each image in the sequence of images. The input image data is processed through a neural network to generate an alternative representation of the input image data. The alternative representation is processed through an output layer to generate an output indicating properties of respective portions of the imaged region.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.