Transgenic mouse expressing human cereblon
US11963520B2 · kind B2 · utility
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7Claims
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Key dates
| Filing date | Jan 18, 2017 |
| Grant date | Apr 23, 2024 |
| Priority date | — |
| Expiry date | Jan 18, 2037 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01K2267/0331
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided are transgenic mice whose genome comprises a nucleic acid sequence encoding human cereblon (CRBN) or a fragment thereof, wherein endogenous mouse CRBN is not expressed in the transgenic mice. Also provided are cells, cell lines, tissues, and organs derivable from the transgenic mice, and methods for producing and using such mice.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.