Deuterated compounds for restoring mutant p53 function
US11963953B2 · kind B2 · utility
1Cited by
3References
33Claims
0Family size
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Key dates
| Filing date | Jan 26, 2023 |
| Grant date | Apr 23, 2024 |
| Priority date | — |
| Expiry date | Jan 26, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B59/002
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The compounds of the current disclosure include propynyl substituted indoles, where one or more hydrido radicals is substituted with a deuterium atom, wherein the compound binds a mutant p53 protein and increases wild-type p53 activity of the mutant p53 protein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.