Patent · US Active

Chimeric antigen receptor

US11963981B2 · kind B2 · utility

0Cited by

4References

16Claims

0Family size

Assignee

AUTOLUS LIMITED · GB

Inventors

Martin Pulé · London, GB
Evangelia Kokalaki · London, GB
Shaun Cordoba · London, GB
Shimobi Onuoha · London, GB
Simon Thomas · London, GB
Biao Ma · Sunnyvale, US
Mathieu Ferrari · London, GB

Key dates

Filing date	May 15, 2019
Grant date	Apr 23, 2024
Priority date	—
Expiry date	Mar 6, 2041

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2510/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides a chimeric antigen receptor (CAR) which binds a target antigen having a bulky extracellular domain, wherein the CAR comprises a Fab antigen binding domain. The present invention also provides nucleic acid sequences and constructs encoding such a CAR, cells expressing such a CAR and their therapeutic uses.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.