Substituted pyridazinone compound and use thereof
US11964962B2 · kind B2 · utility
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Key dates
| Filing date | Dec 14, 2021 |
| Grant date | Apr 23, 2024 |
| Priority date | — |
| Expiry date | Dec 14, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed is a pyridazinone compound represented by Formula (I), or a pharmaceutically acceptable salt, prodrug, hydrate, solvate, polymorph, stereoisomer, or isotopic variant thereof. The compound can be used for preparation of medicinal products for treatment and/or prophylaxis of a disease or condition associated with thyroid hormone abnormalities. The compound has higher selectivity to THβ, better pharmacokinetic parameters, desired stability, and higher agonistic activity toward THβ.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.