Methods and compositions for sensitization of tumor cells to immune therapy
US11965161B2 · kind B2 · utility
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45Claims
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Key dates
| Filing date | Mar 3, 2021 |
| Grant date | Apr 23, 2024 |
| Priority date | — |
| Expiry date | Mar 3, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/31
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are methods and compositions related to the treatment or prevention of cancer (e.g., by targeting a tumor in a subject with cancer) by administering to a subject an agent that inhibits autophagy. In certain aspects, provided herein are methods of compositions related to methods of sensitizing cancer cells to tumor necrosis factor-alpha (TNF-α) mediated killing by contacting the cells or administering the agent that inhibits autophagy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.