Method of quantitating unbound C5 in a sample
US11965884B2 · kind B2 · utility
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9Claims
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Key dates
| Filing date | Oct 19, 2017 |
| Grant date | Apr 23, 2024 |
| Priority date | — |
| Expiry date | Feb 2, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/4716
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of quantitating free (unbound) human C5 complement protein (C5) from a sample comprising: binding biotinylated anti-C5 capture antibody to strepavidin-coated particles; capturing the free (unbound) C5 in the sample; detecting the captured free C5; and quantitating the captured free C5 using laser-induced fluorescence detection; wherein the method is performed in a Gyros Bioaffy 200 CD in a Gyrolab xPlore or a Gyrolab XP instrument.
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