Lipid nanoparticle formulation
US11969506B2 · kind B2 · utility
6Cited by
76References
13Claims
0Family size
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Key dates
| Filing date | Mar 15, 2018 |
| Grant date | Apr 30, 2024 |
| Priority date | — |
| Expiry date | Mar 27, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/32
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The disclosure features novel lipids and compositions involving the same. Nanoparticle compositions include an ionizable lipid, a phospholipid, a first sterol or a tocopherol, and optionally a second sterol different from the first sterol. Nanoparticle compositions further including therapeutic and/or prophylactics such as RNA are useful in the delivery of therapeutic and/or prophylactics to mammalian cells or organs to, for example, regulate polypeptide, protein, or gene expression.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.