Nucleic acid capture, concentration, and purification
US11975325B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 25, 2021 |
| Grant date | May 7, 2024 |
| Priority date | — |
| Expiry date | Feb 17, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6813
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An example of a kit includes a flow cell assembly. The flow cell assembly includes a reaction chamber, a temperature controlled flow channel in selective fluid communication with an inlet of the reaction chamber, and a filter positioned in the temperature controlled flow channel. The reaction chamber includes depressions separated by interstitial regions and capture primers attached within each of the depressions. The filter is i) to block concentrated biological sample-polymer complexes generated in the temperature controlled flow channel at a first temperature, and ii) to allow passage of concentrated biological sample and polymer released from the complexes in the temperature controlled flow channel at a second temperature.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.