Liquid sample loading

US11975328B2 · kind B2 · utility

Assignees

• Illumina, Inc. · US
• Illumina Cambridge Limited · GB

Inventors

• Bradley Kent Drews · San Diego, US
• Gudrun Stengel · San Diego, US
• James Christopher Blake · Village of La Jolla, US
• Mohammed Kafeel Ahamed · Carlsbad, US
• Michael Steven Becker · Del Mar, US
• Michael Dangelo · San Diego, US
• Mark J. Nibbe · San Diego, US
• Daniel L. Fuller · Cambridge, GB
• Oliver Jon Miller · Cambridge, GB

Key dates

• Filing date: Oct 21, 2021
• Grant date: May 7, 2024
• Expiry date: Nov 6, 2041

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B01L2300/0829
• WIPO field: Chemical engineering
• WIPO sector: Chemistry

Abstract

The assembly includes a docking console and a manifold. The docking console includes a cartridge support surface having a first end and a second end. The manifold has one or more wells defined therein. The docking console further includes a manifold retention bracket to releasably hold the manifold against a fluid cartridge supported on the cartridge support surface at an interface position such that the one or more wells are in fluid communication with the fluid cartridge and a biased seal bar to press the fluid cartridge against the manifold held by the manifold retention bracket. A hydrophilic porous frit disposed within at least one of the wells and is to permit liquid to flow through the outlet aperture but prevent gas from passing through the outlet aperture.