Patent · US Active

APOL1 inhibitors and methods of use

US11976067B2 · kind B2 · utility

1Cited by
8References
159Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 17, 2023
Grant dateMay 7, 2024
Priority date
Expiry dateJan 17, 2043

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07B2200/05
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Provided herein are compounds of formula (II): or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing, wherein m, n, p, R1, R2, R3, L1, L2, L3, R4, X1, X2, X3, and X4 are as defined herein. Also provided are methods of preparing compounds of formula (II), or a stereoisomer or tautomer thereof, or a pharmaceutically acceptable salt of any of the foregoing. Also provided are methods of inhibiting APOL1 and methods of treating an APOL1-mediated disease, disorder, or condition in an individual.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.