Patent · US Active

Continuous process for manufacturing alkyl 7-amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridine-carboxylate

US11976082B2 · kind B2 · utility

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1References

19Claims

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Assignee

Boehringer Ingelheim International GmbH · DE

Inventors

Bernd Werner · Pfungstadt, DE
Tobias Alt · Ingelheim am Rhein, DE
Andrew T. Brusoe · New Milford, US
Frederic Buono · Franklin Park, US
Michael Klumb · Mainz, DE
Bjoern Stahl · Ginsheim, DE
Thomas G. Tampone · Southbury, US

Key dates

Filing date	May 21, 2021
Grant date	May 7, 2024
Priority date	—
Expiry date	Dec 1, 2041

Classification

Technology area (CPC B)Performing Operations; Transporting
CPC primaryB01J2219/00162
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

This invention relates to a novel continuous process for making alkyl 7-amino-5-methyl-[1,2,5]-oxadiazolo¬[3,4-b]pyridine-carboxylate,wherein R is C1-3-alkyl. The process of the invention present invention overcomes disadvantages of processes of the prior art by avoiding the highly energetic intermediates, using readily available and inexpensive starting materials and reagents, and avoiding the isolation of intermediates. The process according to the invention is suitable for use on industrial scale.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.