D-psicose crystal and preparation method thereof
US11976090B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 15, 2023 |
| Grant date | May 7, 2024 |
| Priority date | — |
| Expiry date | Jan 15, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H3/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention provides a D-psicose crystal and a preparation method thereof. The method comprises: adding a seed crystal to a D-psicose solution and stirring uniformly, subjecting the solution to crystallization by gradient cooling and constant-temperature crystallization alternately at 50-30° C., stopping the crystallization until the temperature of the solution is 30° C., separating the crystal by centrifugation, washing and drying, to obtain a D-psicose crystal. Rather than evaporative crystallization, organic solvent-assisted crystallization and ultrasonication, controllable crystallization by gradient cooling, constant-temperature crystallization, and other technical means are employed. Thus, the invention has low requirements for equipment, simple process, low energy consumption, and low preparation cost, and thus particularly suitable for large-scale industrial production and processing. The purity of the D-psicose crystal obtained is ≥98.5%, 80% by weight or more of the crystal has a grain size in the range of 20-40 meshes, and the yield per crystallization is ≥70%.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.