Compositions and methods for treatment of bone associated diseases

US11976099B2 · kind B2 · utility

Assignees

• The National Institute for Biotechnology in the Negev Ltd. · IL
• B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY · IL

Inventors

• Niv Papo · Palo Alto, US
• Noam Levaot · Rahat, IL
• Yuval Zur · Netanya, IL
• Lior Rosenfeld · Holon, IL

Key dates

• Filing date: Aug 4, 2021
• Grant date: May 7, 2024
• Expiry date: Oct 22, 2041

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K14/53
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Mutant M-CSF protein, comprising αvβ3 integrin binding motif and pharmaceutical compositions comprising same, are provided. Further, use of the composition for the treatment and or prevention of diseases associated with increased bone resorption are provided.