Image enhancement to enable improved nuclei detection and segmentation
US11978200B2 · kind B2 · utility
1Cited by
7References
20Claims
0Family size
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Key dates
| Filing date | Mar 26, 2021 |
| Grant date | May 7, 2024 |
| Priority date | — |
| Expiry date | Jun 6, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06T2207/30024
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
Aspects of the present disclosure pertain to systems and methods for enhancing brightfield or darkfield images to better enable nucleus detection. In some embodiments, the systems and methods described herein are useful for identifying membrane stain biomarkers as well as nuclear/cytoplasm stain biomarkers in stained images of biological samples. In some embodiments, the presently disclosed systems and methods enable quick and accurate nucleus detection in stained images of biological samples, especially for original stained images of biological samples where the nuclei appear faint.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.