Bacteriophage-derived nanopore sensors
US11980849B2 · kind B2 · utility
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16Claims
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Key dates
| Filing date | Feb 8, 2019 |
| Grant date | May 14, 2024 |
| Priority date | — |
| Expiry date | Jul 4, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/005
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
Disclosed herein are compositions and methods that involve inserting connector protein channels of bacteriophage DNA packaging motors into copolymeric membranes via liposome-polymer fusion, which can be used as nanopore sensors for biomedical applications such as high throughput protein sequencing or cancer diagnosis. For example, disclosed are compositions comprising a copolymeric membrane into which a connector protein channel of a bacteriophage packaging motor has been inserted.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.