Multiplexed microfluidic probe insert for microtiter plates
US11980888B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 1, 2020 |
| Grant date | May 14, 2024 |
| Priority date | — |
| Expiry date | Jun 4, 2042 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2400/049
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A microtiter plate comprising a first array of M×N wells and a microfluidic probe insert is provided. The microfluidic probe insert includes a second array of M×N microfluidic probe conduits, forming N columns of M conduits. The M conduits include respective orifices in a bounding plane and extend, each, perpendicularly to the bounding plane on one side. The microfluidic probe insert also includes N vacuum circuits, each comprising at least one vacuum port and M openings in the bounding plane, where 2≤M, 2≤N. The microfluidic probe insert is positioned on the microtiter plate and the microfluidic probe conduits are inserted in respective wells. A processing liquid is ejected from M conduits via the M orifices of the M conduits by applying a negative pressure to a corresponding set of N vacuum circuits via the respective one or more vacuum ports.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.