Patent · US Active

Compositions for treating neurodegenerative diseases

US11981636B2 · kind B2 · utility

0Cited by
23References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 29, 2021
Grant dateMay 14, 2024
Priority date
Expiry dateNov 29, 2041

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D491/107
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present disclosure relates to novel compounds of Formula I wherein each of Ra, Rb, Rd and Re is independently H; Rc is selected from the group consisting of H, hydroxyl, halo, alkyl, alkoxy, CF3, SO2CH3, and morpholino, R1 is selected from the group consisting of hydrogen, alkyl, phenyl, or —CH═C(CH3)2; and R2 is specific substituted cyclic amino groups. The invention also discloses pharmaceutical compositions containing the compounds and methods of using the compounds and pharmaceutical compositions for treating neurogenerative diseases, including Alzheimer's disease and cognitive decline.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.