Growth hormone receptor antagonists and fusion proteins thereof
US11981719B2 · kind B2 · utility
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1References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 20, 2018 |
| Grant date | May 14, 2024 |
| Priority date | — |
| Expiry date | Apr 10, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/61
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a growth hormone receptor antagonist comprising a growth hormone variant which is modified by substitution of one or more amino acids of growth hormone. Further, the growth hormone receptor antagonist of the present invention may further comprise a long-acting carrier which is fused to the growth hormone variant. The growth hormone receptor antagonist may have strong binding potency to growth hormone receptor and may exhibit a long-lasting antagonistic action.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.