Gene editing methods with increased knock-in efficiency
US11981898B2 · kind B2 · utility
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5Claims
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Key dates
| Filing date | Jun 18, 2018 |
| Grant date | May 14, 2024 |
| Priority date | — |
| Expiry date | Jun 2, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y301/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure provides compositions and methods for targeted insertion of a gene of interest in the genome of a cell using single-stranded DNA or double-stranded DNA with 3 overhang. Also provided are methods of generating single-stranded DNA or double-stranded DNA with 3′ over-hang that can be used for targeted insertion.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.