Cell culture
US11981926B2 · kind B2 · utility
0Cited by
6References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 12, 2021 |
| Grant date | May 14, 2024 |
| Priority date | — |
| Expiry date | Feb 28, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2502/27
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
There is described an isolated 3-dimensional liver spheroid wherein said spheroid has: increased ATP content as compared to a 3-dimensional liver spheroid cultured in Complete William's E medium alone; the same or increased activity of cytochrome P450 1A1 and cytochrome P450 1B1 as compared to a 3-dimensional liver spheroid cultured in Complete William's E medium alone; and increased albumin secretion as compared to a 3-dimensional liver spheroid cultured in William's E medium alone.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.