Stable liquid formula comprising anti-TNFa antibody, acetate buffer, and glycine
US11986523B2 · kind B2 · utility
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5References
14Claims
0Family size
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Key dates
| Filing date | Mar 16, 2021 |
| Grant date | May 21, 2024 |
| Priority date | — |
| Expiry date | Jun 17, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K16/241
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed is a stable liquid formulation, comprising an antibody or antigen-binding portion thereof, an acetate buffer, glycine, and a surfactant, wherein the stable liquid formulation does not comprise at least one of sugar, a sugar alcohol and a metal salt, and the stable liquid formulation is still stable even upon high antibody content, and is superior in osmolality and viscosity, and subcutaneous administration thereof is possible.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.